翻訳と辞書 Words near each other ・ RAF Jurby ・ RAF Jurby Head ・ RAF Kai Tak ・ RAF Kalafrana ・ RAF Kaldadarnes ・ RAF Kalyan ・ RAF Kandahar ・ RAF Keevil ・ RAF Kelstern ・ RAF Kenley ・ RAF Khormaksar ・ RAF Kilchiaran ・ RAF Killadeas ・ RAF Kimbolton ・ RAF kinase ・ Raf kinase inhibitor protein ・ RAF Kings Cliffe ・ RAF Kingsnorth ・ RAF Kingsnorth (World War II) ・ RAF Kinloss ・ RAF Kirkistown ・ RAF Kirknewton ・ RAF Kirmington ・ RAF Kirton in Lindsey ・ RAF Knettishall ・ RAF Kota Bharu ・ RAF Kuala Lumpur ・ RAF Laarbruch ・ RAF Lakenheath ・ RAF Langar Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Raf kinase inhibitor protein ： ウィキペディア英語版 Raf kinase inhibitor protein The Raf kinase inhibitor protein (RKIP) is a kinase inhibitor protein, that regulates many signaling pathways within the cell. RKIP is a member of the phosphatidylethanolamine-binding protein family and has displayed disruptive regulation on the Raf-1-MEK1/2, ERK1/2 and NF-kappaB signalling pathways, by interaction with the Raf-1 kinase. RKIP has also been shown to inhibit G protein coupled receptor kinases (GRK) when phosphorylated by protein kinase C.〔Lorenz K, Lohse MJ, Quitterer U (2003): ''Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2.'' Nature 426: 574-579.〕 Via this mechanism it has been shown to exert beneficial effects on cardiac structure and function.〔Schmid E, Neef S, Berlin C, Tomasovic A, Kahlert K, Nordbeck P, Deiss K, Denzinger S, Herrmann S, Wettwer E, Weidendorfer M, Becker D, Schäfer F, Wagner N, Ergün S, Schmitt JP, Katus HA, Weidemann F, Ravens U, Maack C, Hein L, Ertl G, Müller OJ, Maier LS, Lohse MJ, Lorenz K (2015): ''Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.'' Nature Medicine doi: 10.1038/nm.3972.〕 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Raf kinase inhibitor protein」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.